The Insides™ System

The Insides^™ System

Providing a new standard of care for colorectal surgery patients

The Insides™ System refeeds chyme back into the distal intestine, improving patient health outcomes.
Chyme Reinfusion is recommended by the European Society of Clinical Nutrition and Metabolism (ESPEN) and American Society for Parenteral and Enteral Nutrition (ASPEN) for the nutrition in patients with acute intestinal failure.

The existing literature also favours chyme reinfusion for its ability to restore intestinal continuity, and improve intestinal function, hydration and the nutritional status of the patient. The benefits of chyme reinfusion improves recovery and conditions patients for definitive surgery.

The Insides™ System enables patients to recommence oral feeding and wean off the expensive therapy of parenteral nutrition. This reduces their length of stay in hospital and potential complications.

A world-first device pioneered and co-developed with colorectal surgeons.
The Insides™ System has been developed on the back of 30+ years of clinical experience in gut nutrition, along with research and development from one of Australasia’s top Universities.

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How it works

How it works

Benefits

Benefits

Earlier return to oral feeding¹ – Patients able to recommence oral feeding
Improved nutritional outcome² – Increase in nutritional risk index by 10.9 (± 9.5) with a 85% reduction in intestinal losses
Improved restoration of gut function³ – Limiting gut atrophy and inflammation
Improved renal function^4-5 – Prevents dehydration and reduces the potential for chronic kidney disease
Improved restoration of gut function³ – Limiting gut atrophy and inflammation
liver function^5-6 – 53% reduction in plasma liver test abnormalities
Wean off Parenteral Nutrition⁶ – greater than 91% of patients weaned off parenteral nutrition within a median of 2 days (± 9)

1. Sharma P, Davidson R, Davidson J, Keane C, Liu C, Ritchie SR, et al. Novel chyme reinfusion device for gastrointestinal fistulas and stomas: feasibility study. Br J Surg [Internet]. 2020 Apr 18; Available from:
http://doi.wiley.com/10.1002/bjs.11516
2. Picot D, Layec S, Dussaulx L, Trivin F, Thibault R. Chyme reinfusion in patients with intestinal failure due to temporary double enterostomy: A 15-year prospective cohort in a referral centre. Clin Nutr [Internet]. 2017 Apr;36(2):593–600. Available from: https://linkinghub.elsevier.com/retrieve/pii/
S0261561416300668
3. Pflug AM, Utiyama EM, Fontes B, Faro M, Rasslan S. Continuous reinfusion of succus entericus associated with fistuloclysis in the management of a complex jejunal fistula on the abdominal wall. Int J Surg Case Rep [Internet]. 2013;4(8):716–8. Available from: https://linkinghub.elsevier.com/retrieve/pii/
S221026121300179X
4. Fielding A, Woods R, Moosvi SR, Wharton RQ, Speakman CTM, Kapur S, et al. Renal impairment after ileostomy formation: a frequent event with long‐term consequences. Color Dis [Internet]. 2019 Oct 17;codi.14866. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1
111/codi.14866
5. Dilke, S. M., Gould, L., Yao, M., Souvatzi, M., Stearns, A., Ignjatovic-Wilson, A., Tozer, P., & Vaizey, C. J. (2021). Distal feeding–bowel stimulation to treat short-term or long-term pathology: a systematic review. Frontline Gastroenterology, 12(7), 677–682. https://doi.org/10.1136/flgastro-2019-101359
6. Layec S, Seynhaeve E, Trivin F, Carsin-Mahé M, Dussaulx L, Picot D. Management of entero-atmospheric fistulas by chyme reinfusion: A retrospective study. Clin Nutr [Internet]. 2020 Apr; Available from: https://linkinghub.elsevier.com/retrieve/pii/
S0261561420301485

System Components

System Components

The Insides™ Driver
Connects magnetically to The Insides™ Pump via the outside of the patient’s ostomy appliance whenever the patient needs to power the pump and refeed the content of the ostomy appliance back into their distal intestine.

The Insides™ Pump
Sits within the ostomy appliance, and pumps the chyme into the distal intestine via The Insides™ Tube

The Insides™ Tube
Inserted into the distal intestine and connected to The Insides™ Pump, serving as a conduit for chyme