Liquid Handling Verification

Improve the quality and reproducibility of your ELISAs

Widely used in an array of industries, ELISAs are a powerful quantitative tool. But assay quality is critical and workflow complexity makes them time-consuming to optimize and troubleshoot. Artel can help…

Speed up ELISA development and optimisation
Approximately 40% of ELISAs fail at some point during the assay’s lifetime if these parameters are not managed and well understood. The MVS can help develop the test plan and protocol faster and with more confidence. Whether you are using a manual multichannel pipette or an ALH, you can use the MVS to assess mixing, washing and reagent dispense steps, which can help you get to optimal conditions much faster, thus saving time, reagents, and money.

Troubleshoot ELISAs faster
Do you experience problems with reproducibility, high backgrounds, large CVs, or your standard curve?
The MVS can help with these as well by enabling efficient assessment of a number of factors including:

• Pipetting accuracy (manual and ALH)
• Pipetting technique
• Assay conditions such as various reagent classes (aqueous, glycerin, DMSO), washing and mixing
• Consumables such as disposable tips

Verify proper pipetting technique
The MVS for multichannel pipettes and PCS for single channel pipettes can help here, by enabling quick checks of a scientist’s pipetting technique to ensure that this is not increasing the variability of your ELISA results. Additionally, scientists can get training at Artel or on site at your facility through the Artel comprehensive training program.

Easily ensure accurate and precise volume transfers
The MVS and PCS are great tools to ensure that your pipettes are performing as expected by making it easy to perform weekly, monthly, quarterly, semi-annual, or annual volume verification checks as needed for your regulated or non-regulated lab.

Improve NGS and qPCR assay success rates and boost productivity

Whether part of a discovery or diagnostics program, NGS and qPCR assays are increasingly being used for making critical decisions. Find out how Artel can help ensure the quality of this important data while keeping workflows flowing.

Automate genomic and NGS assays faster
The MVS aids in liquid class optimisation by allowing you to assess volume transfer and mixing at each step of the workflow instead of waiting until the assay is complete. The assay can be optimised more efficiently – saving time, reagents and money.

Ensure regulatory compliance
The MVS is a great tool to ensure that multichannel pipettes and automated liquid handlers are performing consistently by running the QC protocols routinely as mandated by the lab’s regulatory requirements.

Develop and transfer assays efficiently
By ensuring accurate small volume transfers upfront, scientists can accelerate successful assay development. The MVS can help researchers develop new genomic and NGS workflows efficiently. Assay developers can also use the MVS to optimise mixing, leading to improved assay quality and ensuring successful outcomes.

Increase instrument uptime
NGS and other genomics workflows can be complex, and when an automated assay fails, troubleshooting can be time consuming. The MVS can expedite your troubleshooting efforts by quickly evaluating a number of factors including:

• Automated liquid handler accuracy and precision
• Assay conditions such as mixing and serial dilutions
• Assay consumable variability such as disposable tips
• Effect of temperature on reagent dispense

Verify proper pipetting technique with manual genomic assays
Problems with pipetting technique propagate across multi-step procedures, negatively impacting the quality and reproducibility of the final data. The MVS for multichannel pipettes can assess operator performance to ensure all operators are pipetting consistently.

For those steps involving single channel pipettes, the PCS Pipette Calibration System can be used to quickly and easily assess and correct these factors.

Speed up assay automation and ensure performance with streamlined liquid class optimisation

Getting liquid class settings right is a critical, but often neglected aspect of automating an assay that can reduce CVs and improve reproducibility.

The MVS streamlines liquid class optimisation
Optimising liquid classes can seem tedious but with an MVS , the process is fast and straightforward. Simply set up your assay and use the MVS reagent that best mimics your liquid. You can test different liquid class settings and then use the MVS to measure how the setting affects liquid handling accuracy and precision.

Optimising liquid classes gets assays into production faster
Working with well-defined liquid classes can cut the time it takes to get an assay into production and improve assay quality by reducing variability stemming from liquid handling. With an MVS, getting this important step done is transformed from challenge into challenge-solved.

Easily ensure accurate and precise volume transfers
The MVS is a great tool to ensure that your liquid handlers are performing as expected by making it easy to perform weekly, monthly, quarterly, semi-annual, or annual volume verification checks as needed for your regulated or non-regulated lab.

Stay on top of your pipette and automated liquid handler calibrations and verifications

Because data quality depends on the accuracy and precision of liquid handling, keeping handheld pipettes and automated liquid handlers calibrated is critical. Fortunately, this important job doesn’t have to be a lot of work.

Calibration for single-channel pipettes
Increase quality, productivity, and compliance when you manage single-channel pipette calibration with the PCS. Portable and easy-to-use, the PCS out-performs other calibration methods in; consistency, speed, simplicity, accuracy and precision—even at volumes as low as 0.1 µL. The dual-dye ratiometric photometry technology used in the PCS is highly resistant to environmental conditions which ensures accurate volume measurements. The results are traceable to the International System of Units, enabling straightforward comparison of pipettes, operators, methods, and locations.

Calibration for multi-channel pipettes
Calibrating multi-channel pipettes can be an especially time-consuming task, with some labs sacrificing the ability to calibrate each individual channel for speed. With the MVS , you can turn a one-hour or more ordeal into a fast 5-minute process with simultaneous measurement of each channel on a multi-channel pipette. Based on the same robust dual-dye ratiometric photometry technology used in the PCS, the MVS brings all the advantages of the PCS to multi-channel pipette calibration.